Literature summary for 2.3.1.7 extracted from

Cordente, A.G.; Swiegers, J.H.; Hegardt, F.G.; Pretorius, I.S.
Modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae (2007), FEMS Microbiol. Lett., 267, 159-166.

Application

Application	Comment	Organism
food industry	modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae	Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment)	Organism
overexpressing CAT2, which encodes the major mitochondrial and peroxisomal carnitine acetyltransferase, on the formation of esters and other flavour compounds during fermentation and overexpression of a modified CAT2 that results in a protein that localizes to the cytosol. The overexpression of both forms of CAT2 resulted in a reduction in ester concentrations, especially in ethyl acetate and isoamyl acetate	Saccharomyces cerevisiae

Cloned (Comment)

Organism

overexpressing CAT2, which encodes the major mitochondrial and peroxisomal carnitine acetyltransferase, on the formation of esters and other flavour compounds during fermentation and overexpression of a modified CAT2 that results in a protein that localizes to the cytosol. The overexpression of both forms of CAT2 resulted in a reduction in ester concentrations, especially in ethyl acetate and isoamyl acetate

Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acetyl-CoA + carnitine	Saccharomyces cerevisiae	this reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell	CoA + O-acetylcarnitine	-	?
additional information	Saccharomyces cerevisiae	carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-
Saccharomyces cerevisiae	P32796	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
acetyl-CoA + carnitine	-	Saccharomyces cerevisiae	CoA + O-acetylcarnitine	-	?
acetyl-CoA + carnitine	this reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell	Saccharomyces cerevisiae	CoA + O-acetylcarnitine	-	?
additional information	carnitine acetyltransferases catalyse the reversible reaction between carnitine and acetyl-CoA to form acetylcarnitine and free CoA. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell	Saccharomyces cerevisiae	?	-	?

Synonyms

Synonyms	Comment	Organism
CAT2	-	Saccharomyces cerevisiae