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Literature summary for 2.3.1.61 extracted from

  • Nakano, K.; Takase, C.; Sakamoto, T.; Nakagawa, S.; Inazawa, J.; Ohta, S.; Matuda, S.
    Isolation, characterization and structural organization of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex (1994), Eur. J. Biochem., 224, 179-189.
    View publication on PubMed
Search for more literature for 2.3.1.61

Application

Application Comment Organism
medicine possible relationship between enzyme and familial Alzheimer's disease is discussed Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
isolation of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex from a human genomic DNA library, cloning vector lambda EMBL3 subcloned into plasmid vector pUC18, gene is located on chromosome 14 at q24.2-q24.3, pseudogene is located on chromosome at p31 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
succinyl-CoA + dihydrolipoamide Homo sapiens
-
 CoA + S-succinyldihydrolipoamide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood peripheral blood cells Homo sapiens
-
fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-CoA + dihydrolipoamide
-
 Homo sapiens CoA + S-succinyldihydrolipoamide
-
 ?