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Literature summary for 2.3.1.6 extracted from

  • Ray, B.; Simon, J.R.; Lahiri, D.K.
    Determination of high-affinity choline uptake (HACU) and choline acetyltransferase (ChAT) activity in the same population of cultured cells (2009), Brain Res., 1297, 160-168.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + choline Homo sapiens formation of acetylcholine in cholinergic neurons largely depends on both the levels of choline being transported into the cells from the extracellular space and the activity of ChAT, kinetics of choline uptake in the SK-N-SH cells CoA + O-acetylcholine acetylcholine is the neurotransmitter used by cholinergic neurons ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Homo sapiens
-
neuroblastoma cell
-
 Homo sapiens
-
neuron cholinergic Homo sapiens
-
SK-N-SH cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
-
 Homo sapiens CoA + O-acetylcholine
-
 ?
acetyl-CoA + choline formation of acetylcholine in cholinergic neurons largely depends on both the levels of choline being transported into the cells from the extracellular space and the activity of ChAT, kinetics of choline uptake in the SK-N-SH cells Homo sapiens CoA + O-acetylcholine acetylcholine is the neurotransmitter used by cholinergic neurons ?

Synonyms

Synonyms Comment Organism
ChAT
-
 Homo sapiens
choline acetyltransferase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Homo sapiens