Literature summary for 2.3.1.6 extracted from

Haugaard, N.; Levin, R.M.
Regulation of the activity of choline acetyl transferase by lipoic acid (2000), Mol. Cell. Biochem., 213, 61-63.

Search for more literature for 2.3.1.6

Activating Compound

Activating Compound	Comment	Organism	Structure
dihydrolipoic acid	it is proposed that dihydrolipoic acid serves an essential role in the regulation of the activity of the the enzyme and that the ratio of reduced to oxidized lipoic acid in the cell may play an important role in the regulation of the activity of the enzyme	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
thioctic acid	it is proposed that dihydrolipoic acid serves an essential role in the regulation of the activity of the the enzyme and that the ratio of reduced to oxidized lipoic acid in the cell may play an important role in the regulation of the activity of the enzyme	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + choline	-	Bos taurus	acetylcholine + CoA	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.8	-	thioctic acid	-	Bos taurus

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Release 2023.1 (January 2023)