Cloned (Comment) | Organism |
---|---|
expression in Chineses hamster ovary cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
140delF | 34.8% of wild-type activity | Homo sapiens |
221delGT | 5% of wild-type activity | Homo sapiens |
252delMRT | 3.2% of wild-type activity | Homo sapiens |
A239V | 90% of wild-type activity | Homo sapiens |
D180fsX251 | 7.7% of wild-type activity | Homo sapiens |
G136R | 40.3% of wild-type activity | Homo sapiens |
L228P | 23.7% of wild-type activity | Homo sapiens |
R68X | 14.2% of wild-type activity | Homo sapiens |
V167fsX228 | 14.9% of wild-type activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | Homo sapiens | reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy | Homo sapiens | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? | |
arachidonoyl-CoA + 1-oleoyl-glycerol-3-phosphate | - |
Homo sapiens | 1-oleoyl-2-arachidonoyl-glycerol-3-phosphate + CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
1-acylglycerol-3-phosphate-O-acyltransferase 2 | - |
Homo sapiens |
AGPAT2 | - |
Homo sapiens |