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Literature summary for 2.3.1.5 extracted from

  • Lo, H.H.; Hsieh, S.E.; Tsai, K.J.; Chung, J.G.
    The effects of ellagic acid on arylamine N-acetyltransferase activity in the bacterium Pseudomonas aeruginosa (1999), Drug Chem. Toxicol., 22, 555-562.
    View publication on PubMed
Search for more literature for 2.3.1.5

Inhibitors

Inhibitors Comment Organism Structure
ellagic acid 48.9% to 80.3% inhibition of the enzyme activity in the intact cell, time- and dose-dependent inhibition, ellagic acid suppresses enzyme activity in six clinically isolated Pseudomonas aeruginosa strains Pseudomonas aeruginosa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000153
-
 2-Aminofluorene
-
 Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
 strain ATCC 27853
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 intact cell: 1.37 nmol/min/10 000 000 000 CFU Pseudomonas aeruginosa
additional information
-
 Vmax 2-aminofluorene: 0.01715, in the presence of ellagic acid: 0.001732 Pseudomonas aeruginosa
0.000592
-
 cytosol, 37°C Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 2-aminofluorene
-
 Pseudomonas aeruginosa CoA + N-acetyl-2-aminofluorene
-
 ?