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Literature summary for 2.3.1.5 extracted from
- N-Acylation of tyramines: purification and characterization of an arylamine N-acetyltransferase from rat brain and liver (1979), Can. J. Biochem., 57, 1204-1209.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
acetyl-CoA | - |
Rattus norvegicus |  |
| 0.08 | - |
octylamine | - |
Rattus norvegicus | |
| 0.08 | - |
3-tyramine | - |
Rattus norvegicus | |
| 0.11 | 0.125 | serotonin | brain | Rattus norvegicus | |
| 0.14 | 0.145 | p-tyramine | - |
Rattus norvegicus | |
| 0.18 | - |
Phenylethylamine | - |
Rattus norvegicus | |
| 0.28 | 0.37 | 4-nitroaniline | - |
Rattus norvegicus | |
| 0.3 | - |
Phenylethylamine | - |
Rattus norvegicus | |
| 1.3 | - |
p-octopamine | liver | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 25000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Wistar | - |
| Rattus norvegicus Wistar | - |
Wistar | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | extrapineal distribution | Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| additional information | in rat tissues | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + 3-tyramine | - |
Rattus norvegicus | CoA + N-acetyl-3-tyramine | - |
? | |
| acetyl-CoA + 4-nitroaniline | - |
Rattus norvegicus | CoA + 4-nitroacetanilide | - |
? | |
| acetyl-CoA + beta-phenylethylamine | - |
Rattus norvegicus | CoA + N-(2-phenylethyl)-acetaminde | - |
? | |
| acetyl-CoA + beta-phenylethylamine | - |
Rattus norvegicus Wistar | CoA + N-(2-phenylethyl)-acetaminde | - |
? | |
| acetyl-CoA + octylamine | - |
Rattus norvegicus | CoA + N-acetyloctylamine | - |
? | |
| acetyl-CoA + p-octopamine | - |
Rattus norvegicus | CoA + N-acetyloctopamine | - |
? | |
| acetyl-CoA + p-octopamine | - |
Rattus norvegicus Wistar | CoA + N-acetyloctopamine | - |
? | |
| acetyl-CoA + p-tyramine | - |
Rattus norvegicus | CoA + N-acetyl-p-tyramine | - |
? | |
| acetyl-CoA + p-tyramine | - |
Rattus norvegicus Wistar | CoA + N-acetyl-p-tyramine | - |
? | |
| acetyl-CoA + serotonin | - |
Rattus norvegicus | CoA + N-acetylserotonin | - |
? | |
| acetyl-CoA + serotonin | - |
Rattus norvegicus Wistar | CoA + N-acetylserotonin | - |
? | |
| acetyl-CoA + tryptamine | - |
Rattus norvegicus | CoA + N-acetyltryptamine | - |
? | |
| acetyl-CoA + tryptamine | - |
Rattus norvegicus Wistar | CoA + N-acetyltryptamine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
tyramine in phosphate buffer | Rattus norvegicus |
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