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Literature summary for 2.3.1.48 extracted from
- The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats (2008), J. Clin. Invest., 118, 868-878.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. Therefore, inhibition of p300 HAT activity by the nontoxic dietary compound curcumin may provide a novel therapeutic strategy for heart failure in humans | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| curcumin | - |
Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cardiomyocyte | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HAT | - |
Rattus norvegicus |
| histone acetyltransferase | - |
Rattus norvegicus |
| p300 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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