Cloned (Comment) | Organism |
---|---|
expression of isoforms ACAT1 and ACAT2 in CHO cell | Chlorocebus aethiops |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aurasperone A | isolation from the culture broth of Aspergillus species; isolation from the culture broth of Aspergillus species | Chlorocebus aethiops | |
aurasperone D | isolation from the culture broth of Aspergillus species; isolation from the culture broth of Aspergillus species | Chlorocebus aethiops | |
averufanin | isolation from the culture broth of Aspergillus species; isolation from the culture broth of Aspergillus species | Chlorocebus aethiops | |
flavasperone | isolation from the culture broth of Aspergillus species, selective for isoform ACAT2 | Chlorocebus aethiops | |
sterigmatocystin | isolation from the culture broth of Aspergillus species, selective for isoform ACAT2 | Chlorocebus aethiops |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chlorocebus aethiops | O77759 | isoform ACAT2 | - |
Chlorocebus aethiops | O77760 | isoform ACAT1 | - |
Source Tissue | Comment | Organism | Textmining |
---|
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0015 | - |
isoform ACAT2, 37°C, cell-based assay | Chlorocebus aethiops | aurasperone A | |
0.0015 | - |
isoform ACAT2, 37°C, cell-based assay | Chlorocebus aethiops | aurasperone D | |
0.0024 | - |
isoform ACAT2, 37°C, cell-based assay | Chlorocebus aethiops | sterigmatocystin | |
0.006 | - |
isoform ACAT1, 37°C, cell-based assay | Chlorocebus aethiops | aurasperone A | |
0.006 | - |
isoform ACAT2, 37°C, cell-based assay | Chlorocebus aethiops | flavasperone | |
0.007 | - |
isoform ACAT1, 37°C, cell-based assay | Chlorocebus aethiops | aurasperone D | |
0.012 | - |
isoform ACAT2, 37°C, cell-based assay | Chlorocebus aethiops | averufanin | |
0.0218 | - |
isoform ACAT1, 37°C, cell-based assay | Chlorocebus aethiops | averufanin | |
0.03 | - |
isoform ACAT1, 37°C, cell-based assay | Chlorocebus aethiops | sterigmatocystin |