Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | poly(ADP-ribose) polymerase inhibition in foam cells resulted in significant sensitization to 7-ketocholesterol by increasing cellular-toxic-free cholesterol, potentially through a down-regulation of ACAT-1 expression | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | Mus musculus | - |
CoA + cholesterol ester | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | - |
Mus musculus | - |
foam cell | - |
Mus musculus | - |
smooth muscle cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | - |
Mus musculus | CoA + cholesterol ester | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACAT-1 | - |
Mus musculus |