Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | Homo sapiens | ACAT-1 plays an important role in the formation of macrophage-derived foam cells in atherosclerotic lesions | CoA + cholesterol ester | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P35610 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | serotonin upregiulates ACAT-1 expression in human monocyte-macrophages | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | ACAT-1 plays an important role in the formation of macrophage-derived foam cells in atherosclerotic lesions | Homo sapiens | CoA + cholesterol ester | - |
? | |
oleoyl-CoA + cholesterol | - |
Homo sapiens | CoA + cholesteryl oleate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACAT-1 | - |
Homo sapiens |
acyl-coenzyme A:cholesterol acyltransferase-1 | - |
Homo sapiens |