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Literature summary for 2.3.1.26 extracted from

  • Lin, S.; Lu, X.; Chang, C.C.; Chang, T.Y.
    Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location (2003), Mol. Biol. Cell, 14, 2447-2460.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.26

Protein Variants

Protein Variants Comment Organism
H434A almost complete loss of activity Homo sapiens
H434N almost complete loss of activity Homo sapiens
additional information insertion of two different antigenic tags at various hydrophilic regions flanking each of the predicted transmembrane domains, analysis indicates that the enzyme contains only 2 detectable transmembrane domains, located near the N-terminal region Homo sapiens
S245A no loss of activity Homo sapiens
S245L about 40% loss of activity Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 expression in chinese hamster ovary cells, isoform ACAT2
-

Source Tissue

Source Tissue Comment Organism Textmining