Activating Compound | Comment | Organism | Structure |
---|---|---|---|
albumin | stimulates, effect is dependent on oleoyl-CoA concentration | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
long-chain fatty acyl-CoA + cholesterol | Homo sapiens | the high activity of intestinal enzyme renders it possible that the enzyme plays a role in cholesterol absorption | CoA + cholesteryl long-chain fatty acyl ester | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
duodenum | - |
Homo sapiens | - |
ileum | - |
Homo sapiens | - |
jejunum | microsomal preparation, highest activity | Homo sapiens | - |
small intestine mucosa | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00005 | - |
whole homogenate of biopsies from distal duodenum-proximal jejunum | Homo sapiens |
0.000053 | - |
microsomal preparations from ileum, mean value | Homo sapiens |
0.000062 | - |
microsomal preparations from duodenum, mean value | Homo sapiens |
0.00021 | - |
microsomal preparations from jejunum, mean value | Homo sapiens |
Storage Stability | Organism |
---|---|
-70°C, biopsies, potassium phosphate buffer, stable for at least 3 years | Homo sapiens |
-70°C, microsomal preparations, stable for up to 1.5 years | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + cholesterol | - |
Homo sapiens | CoA + cholesterol ester | - |
? | |
long-chain fatty acyl-CoA + cholesterol | the high activity of intestinal enzyme renders it possible that the enzyme plays a role in cholesterol absorption | Homo sapiens | CoA + cholesteryl long-chain fatty acyl ester | - |
? | |
oleoyl-CoA + cholesterol | - |
Homo sapiens | CoA + cholesteryl oleate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.4 | pH 6.5: 55% of activity maximum, pH 8.4: 75% of activity maximum | Homo sapiens |