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Literature summary for 2.3.1.21 extracted from

  • Zheng, J.; Luo, Z.; Zhu, Q.; Chen, Q.; Gong, Y.
    Molecular characterization, Tissue distribution and kinetic analysis of carnitine palmitoyltransferase I in juvenile yellow catfish Pelteobagrus fulvidraco (2013), Genomics, 101, 195-203.
    View publication on PubMed
Search for more literature for 2.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
malonyl-CoA complete inhibition at 0.05 mM; complete inhibition at 0.05 mM; complete inhibition at 0.05 mM; complete inhibition at 0.05 mM Tachysurus fulvidraco

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0127
-
 palmitoyl-CoA enzyme from intestine, at pH 8.0 and 37°C Tachysurus fulvidraco
0.0137
-
 palmitoyl-CoA enzyme from heart, at pH 8.0 and 37°C Tachysurus fulvidraco
0.014
-
 palmitoyl-CoA enzyme from muscle, at pH 8.0 and 37°C Tachysurus fulvidraco
0.0159
-
 palmitoyl-CoA enzyme from liver, at pH 8.0 and 37°C Tachysurus fulvidraco
0.0167
-
 palmitoyl-CoA enzyme from spleen, at pH 8.0 and 37°C Tachysurus fulvidraco
0.69
-
 L-carnitine enzyme from spleen, at pH 8.0 and 37°C Tachysurus fulvidraco
0.93
-
 L-carnitine enzyme from muscle, at pH 8.0 and 37°C Tachysurus fulvidraco
0.98
-
 L-carnitine enzyme from heart, at pH 8.0 and 37°C Tachysurus fulvidraco
1.16
-
 L-carnitine enzyme from liver, at pH 8.0 and 37°C Tachysurus fulvidraco
1.34
-
 L-carnitine enzyme from intestine, at pH 8.0 and 37°C Tachysurus fulvidraco

Localization

Localization Comment Organism GeneOntology No. Textmining
outer mitochondrial membrane
-
 Tachysurus fulvidraco
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + L-carnitine Tachysurus fulvidraco
-
 CoA + L-palmitoylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Tachysurus fulvidraco M4H3I4 yellow catfish
-
Tachysurus fulvidraco M4H3S7 yellow catfish
-
Tachysurus fulvidraco M4H428 yellow catfish
-
Tachysurus fulvidraco M4H4E4 yellow catfish
-

Source Tissue

Source Tissue Comment Organism Textmining
heart highest activity in liver and heart Tachysurus fulvidraco
-
intestine
-
 Tachysurus fulvidraco
-
juvenile
-
 Tachysurus fulvidraco
-
liver highest activity in liver and heart Tachysurus fulvidraco
-
mesenteric adipose tissue
-
 Tachysurus fulvidraco
-
spleen lowest activity in muscle and spleen Tachysurus fulvidraco
-
white muscle lowest activity in muscle and spleen Tachysurus fulvidraco
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + L-carnitine
-
 Tachysurus fulvidraco CoA + L-palmitoylcarnitine
-
 ?

Synonyms

Synonyms Comment Organism
carnitine palmitoyltransferase I
-
 Tachysurus fulvidraco
CPT Ialpha1a isoform Tachysurus fulvidraco
CPT Ialpha1b isoform Tachysurus fulvidraco
CPT Ialpha2a isoform Tachysurus fulvidraco
CPT Ibeta isoform Tachysurus fulvidraco