Cloned (Comment) | Organism |
---|---|
gene cpt1c, expression in HEK-293T cells | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | disruption of the cpt1c gene results in lower body weight and decreased food intake, construction of CPT1c knockout mice, which exhibit decreased rates of fatty acid oxidation, which may contribute to their increased susceptibility to diet-induced obesity, overview | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
malonyl-CoA | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial outer membrane | - |
Mus musculus | 5741 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | CPT1c is necessary for the regulation of energy homeostasis, and does not catalyze acyl transfer from various fatty acyl-CoAs to carnitine | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
gene cpt1c, brain-specific isozyme CPT1c | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | brain-specific isozyme | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CPT1c is necessary for the regulation of energy homeostasis, and does not catalyze acyl transfer from various fatty acyl-CoAs to carnitine | Mus musculus | ? | - |
? | |
additional information | the brain-specific isozyme CPT1c has a unique function or activation mechanism, and does not catalyze acyl transfer from various fatty acyl-CoAs to carnitine, no activity with diverse acyl-CoAs, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carnitine palmitoyltransferase-1c | - |
Mus musculus |
CPT1c | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |