Cloned (Comment) | Organism |
---|---|
expression of L-CPT I in Saccharomyces cerevisiae, recombinant and native enzyme show the same biochemical properties | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
malonyl-CoA | L-CPT I, recombinant enzyme from Saccharomyces cerevisiae is inhibited only in intact mitochondria, not as solubilized enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial outer membrane | L-CPT I in outer membrane, native and recombinant in Saccharomyces cerevisiae | Rattus norvegicus | 5741 | - |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Rattus norvegicus | - |
CoA + L-acylcarnitine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
L-CPT I | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | L-CPT I | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0013 | - |
native L-CPT I in liver mitochondria | Rattus norvegicus |
0.0032 | - |
mitochondrial fraction of recombinant Saccharomyces cerevisiae expressing L-CPT I | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-acylcarnitine | - |
? | |
palmitoyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-palmitoylcarnitine | - |
? |