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Literature summary for 2.3.1.21 extracted from

  • Declercq, P.E.; Falck, J.R.; Kuwajima, M.; Tyminski, H.; Foster, D.W.; McGarry, J.D.
    Characterization of the mitochondrial carnitine palmitoyltransferase enzyme system. I. Use of inhibitors (1987), J. Biol. Chem., 262, 9812-9821.
    View publication on PubMed
Search for more literature for 2.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
2-bromopalmitoyl-CoA irreversible; with addition of carnitine Rattus norvegicus
malonyl-CoA reversible inhibition Rattus norvegicus
tetradecylglycidyl-CoA and analogues, irreversible Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial inner membrane inner face of inner membrane Rattus norvegicus 5743
-
mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
86000
-
 1 * 86000, muscle, SDS-PAGE Rattus norvegicus
94000
-
 1 * 94000, liver, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
skeletal muscle
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 r
palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 r

Subunits

Subunits Comment Organism
monomer 1 * 94000, liver, SDS-PAGE Rattus norvegicus
monomer 1 * 86000, muscle, SDS-PAGE Rattus norvegicus