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Literature summary for 2.3.1.21 extracted from

  • McCormick, K.; Notar-Francesco, V.J.
    Importance of albumin binding in the assay for carnitine palmitoyltransferase (1983), Biochem. J., 216, 495-498.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.21

Activating Compound

Activating Compound Comment Organism Structure
salicylic acid activates best at 20 mM, pH changes Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
palmitoyl-CoA substrate inhibition Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information alterations in long-chain acyl-CoA binding to albumin in the CPT assay appreciablly affect the reaction at commonly used substrate concentrations Rattus norvegicus
0.047
-
 palmitoyl-CoA
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus
0.001
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?
palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 ?