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Literature summary for 2.3.1.21 extracted from

  • Kerner, J.; Bieber, L.
    Isolation of a malonyl-CoA-sensitive CPT/beta-oxidation enzyme complex from heart mitochondria (1990), Biochemistry, 29, 4326-4334.
    View publication on PubMed
Search for more literature for 2.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
malonyl-CoA CPT II not inhibited; mitochondrial isozyme CPT I, sensitivity against malonyl-CoA is mediated by a 86 kDa malonyl-CoA binding protein complexed with CPT and other proteins of the beta-oxidation, detergent and salt sensitive Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
-
 Bos taurus
68000
-
 x * 68000, SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Bos taurus
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 enzyme forms CPTi and CPTo
-

Purification (Commentary)

Purification (Comment) Organism
CPTo Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine
-
 ?
decanoyl-CoA + L-carnitine
-
 Bos taurus CoA + L-decanoylcarnitine
-
 ?

Subunits

Subunits Comment Organism
? x * 68000, SDS-PAGE Bos taurus
More CPTo and CPTi are associated with a complex that contains beta-oxidation enzymes Bos taurus