Literature summary for 2.3.1.20 extracted from

Cheng, D.; Meegalla, R.L.; He, B.; Cromley, D.A.; Billheimer, J.T.; Young, P.R.
Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein (2001), Biochem. J., 359, 707-714.

Search for more literature for 2.3.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
DGATsv, splice variant, deletion of 101 residues from the C-terminus, enzymatically inactive	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
50000	-	4 * 50000, SDS-PAGE	Homo sapiens
150000	-	gel filtration	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acyl-CoA + 1,2-diacylglycerol	Homo sapiens	last step of triacylglycerol synthesis	CoA + triacylglycerol	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adipocyte	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.0035	0.0134	transfected cells	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyl-CoA + 1,2-diacylglycerol	-	Homo sapiens	CoA + triacylglycerol	-	?
acyl-CoA + 1,2-diacylglycerol	last step of triacylglycerol synthesis	Homo sapiens	CoA + triacylglycerol	-	?

Subunits

Subunits	Comment	Organism
tetramer	4 * 50000, SDS-PAGE	Homo sapiens

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Release 2023.1 (January 2023)