Cloned (Comment) | Organism |
---|---|
overexpressed in Escherichia coli DH10B cells using the pET30 vector, selenomethionine-substituted protein expressed in Escherichia coli BL21(DE3) | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(2-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea | - |
Escherichia coli | |
1-(3,5-dibromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(4-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(2-bromophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(2-chlorophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(2-fluorophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(4-bromophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(4-chlorophenyl)-3-phenylurea | - |
Escherichia coli | |
1-(5-bromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity in three chromatographic steps (Q-Sepharose, MonoQ, and hydroxyapatite) | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
malonyl-ACP + acetyl-CoA | - |
Escherichia coli | CO2 + CoA + acetoacetyl-ACP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-ketoacyl-acyl carrier protein synthase III | - |
Escherichia coli |
FabH | - |
Escherichia coli |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0047 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(4-chlorophenyl)-3-phenylurea | |
0.0066 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea | |
0.0101 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(4-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea | |
0.0218 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(2-chlorophenyl)-3-phenylurea | |
0.0374 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(2-fluorophenyl)-3-phenylurea | |
0.041 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(4-bromophenyl)-3-phenylurea | |
0.0515 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(2-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea | |
0.0564 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(5-bromo-2-hydroxybenzyl)-1-(2-bromophenyl)-3-phenylurea | |
0.0717 | - |
pH 7.0, temperature not specified in the publication | Escherichia coli | 1-(3,5-dibromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea |