Cloned (Comment) | Organism |
---|---|
His-tagged protein expressed in Escherichia coli BL21(DE3) | Streptococcus pneumoniae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cerulenin | blocking active site cysteine | Streptococcus pneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
immobilized metal ion affinity chromatography (Ni2+) | Streptococcus pneumoniae |
Synonyms | Comment | Organism |
---|---|---|
FabF | - |
Streptococcus pneumoniae |
FabF elongation condensing enzyme | - |
Streptococcus pneumoniae |
General Information | Comment | Organism |
---|---|---|
malfunction | endogenous H2O2 (mainly produced by pyruvate oxidase) inhibits FabF activity by specifically oxidizing its active site cysteine-thiol residue | Streptococcus pneumoniae |