Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.167 extracted from

  • Ondari, M.E.; Walker, K.D.
    The taxol pathway 10-O-acetyltransferase shows regioselective promiscuity with the oxetane hydroxyl of 4-deacetyltaxanes (2008), J. Am. Chem. Soc., 130, 17187-17194.
    View publication on PubMed
Search for more literature for 2.3.1.167

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0576
-
 10-deacetylbaccatin III
-
 Taxus cuspidata

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 SDS-PAGE Taxus cuspidata

Organism

Organism UniProt Comment Textmining
Taxus cuspidata
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Taxus cuspidata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 10-deacetylbaccatin III
-
 Taxus cuspidata CoA + baccatin III
-
 ?
acetyl-CoA + 4-deacetylbaccatin III
-
 Taxus cuspidata CoA + baccatin III
-
 ?
acetyl-CoA + 7,13-diacetyl-4-deacetylbaccatin III
-
 Taxus cuspidata CoA + 13-acetylbaccatin III
-
 ?

Synonyms

Synonyms Comment Organism
10-deacetylbaccatin III:10beta-O-acetyltransferase
-
 Taxus cuspidata
10beta-O-acetyltransferase
-
 Taxus cuspidata
DBAT
-
 Taxus cuspidata

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.58
-
 10-deacetylbaccatin III
-
 Taxus cuspidata

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Taxus cuspidata

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.015
-
 7,13-diacetyl-4-deacetylbaccatin III
-
 Taxus cuspidata
0.19
-
 4-deacetylbaccatin III
-
 Taxus cuspidata
10.07
-
 10-deacetylbaccatin III
-
 Taxus cuspidata