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Literature summary for 2.3.1.15 extracted from

  • Nagle, C.A.; Vergnes, L.; Dejong, H.; Wang, S.; Lewin, T.M.; Reue, K.; Coleman, R.A.
    Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice (2008), J. Lipid Res., 49, 823-831.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.15

Application

Application Comment Organism
medicine elucidation of the metabolic pathways of triacylglycerol is critical to the understanding of chronic metabolic disorders such as obesity, cardiovascular disease and diabetes Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + sn-glycerol 3-phosphate Mus musculus
-
 CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brown adipose tissue
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + sn-glycerol 3-phosphate
-
 Mus musculus CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
fatty acyl-CoA + glycerol-3-phosphate
-
 Mus musculus CoA + lysophosphatidic acid
-
 ?

Synonyms

Synonyms Comment Organism
AGPAT6
-
 Mus musculus
GPAT
-
 Mus musculus
GPAT4
-
 Mus musculus
sn-glycerol-3-phosphate acyltransferase
-
 Mus musculus