Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Polymyxin B | activation of mitochondrial enzyme, inhibition of microsomal enzyme | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Bromelain | strong inhibition of microsomal enzyme | Rattus norvegicus | |
deoxycholate | - |
Rattus norvegicus | |
additional information | mitochondrial enzyme, not inhibited by bromelain, papain, pronase and trypsin | Rattus norvegicus | |
papain | strong inhibition of microsomal enzyme | Rattus norvegicus | |
Polymyxin B | 0.5 mg/ml, approx. 75% inhibition of microsomal enzyme, slight stimulation of mitochondrial enzyme | Rattus norvegicus | |
Pronase | strong inhibition of microsomal enzyme | Rattus norvegicus | |
Triton X-100 | - |
Rattus norvegicus | |
Trypsin | 0.04 mg/ml, approx. 80% inhibition of microsomal enzyme within 3 min at 37°C, inhibition of the mitochondrial enzyme only in the presence of 0.05% deoxycholate or 0.1% Triton X-100 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male | - |
Rattus norvegicus | - |
Sprague-Dawley strain | - |
Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley strain | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
4-6°C, microsomal enzyme, t1/2: 4 h | Rattus norvegicus |
4-6°C, mitochondrial enzyme, 4 h, no loss of activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
oleoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus | CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
? | |
oleoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus Sprague-Dawley | CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
? | |
palmitoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus | CoA + 1-palmitoyl-sn-glycerol 3-phosphate | - |
? | |
palmitoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus Sprague-Dawley | CoA + 1-palmitoyl-sn-glycerol 3-phosphate | - |
? |