Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8K341 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | - |
Mus musculus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | protein p27Kip1 controls the transport of vesicles and organelles along the axon of mice cortical projection neurons in vitro. p27Kip1 stabilizes the alpha-tubulin acetyltransferase 1, thereby promoting the acetylation of microtubules. Cortical extracts isolated from P0 p27Kip1 KO mice show a reduced level of acetylated alpha-tubulin, and the protein level of Atat1 is reduced upon loss of p27Kip1 | Mus musculus |