Literature summary for 2.2.1.7 extracted from

Xu, Y.; Liu, J.; Liang, L.; Yang, X.; Zhang, Z.; Gao, Z.; Sui, C.; Wei, J.
Molecular cloning and characterization of three cDNAs encoding 1-deoxy-D-xylulose-5-phosphate synthase in Aquilaria sinensis (Lour.) Gilg. (2014), Plant Physiol. Biochem., 82, 133-141.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain EcAB4-2	Aquilaria sinensis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
pyruvate + D-glyceraldehyde 3-phosphate	Aquilaria sinensis	-	1-deoxy-D-xylulose 5-phosphate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Aquilaria sinensis	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Aquilaria sinensis	-
root	-	Aquilaria sinensis	-
stem	highest expression	Aquilaria sinensis	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pyruvate + D-glyceraldehyde 3-phosphate	-	Aquilaria sinensis	1-deoxy-D-xylulose 5-phosphate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
DXS1	isoform	Aquilaria sinensis
DXS2	isoform	Aquilaria sinensis
DXS3	isoform	Aquilaria sinensis

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	-	Aquilaria sinensis

Expression

Organism	Comment	Expression
Aquilaria sinensis	isoform DXS1 expression is stimulated by mechanical, chemical, and H2O2 treatment, while isoforms DXS2 and DXS3 only respond to chemical treatment and mechanical treatment, respectively. All isoforms are upregulated after methyl jasmonate treatment	up

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Release 2023.1 (January 2023)