Literature summary for 2.2.1.6 extracted from

Kaloumenos, N.; Dordas, C.; Diamantidis, G.; Eleftherohorinos, I.
Multiple Pro197 substitutions in the acetolactate synthase of corn poppy (Papaver rhoeas) confer resistance to tribenuron (2009), Weed Sci., 57, 362-368.

Protein Variants

Protein Variants	Comment	Organism
additional information	among 28 populations resistant to herbiced tribenuron, nine individuals have only the mutant ALS gene and are homozygous, 18 individuals have both the wild type and the mutant ALS gene and are heterozygous, whereas one individual is heterozygous but with two different mutant ALS alleles	Papaver rhoeas
P197A	mutation confers resistance to herbicide tribenuron. Mutation results in altered secondary structure, which stabilizes an ALS tertiary conformation that prevents tribenuron binding. Most common mutation among 28 populations resistant to tribenuron	Papaver rhoeas
P197L	mutation confers resistance to herbicide tribenuron. Mutation results in altered secondary structure, which stabilizes an ALS tertiary conformation that prevents tribenuron binding	Papaver rhoeas
P197R	mutation confers resistance to herbicide tribenuron. Mutation results in altered secondary structure, which stabilizes an ALS tertiary conformation that prevents tribenuron binding	Papaver rhoeas
P197S	mutation confers resistance to herbicide tribenuron. Mutation results in altered secondary structure, which stabilizes an ALS tertiary conformation that prevents tribenuron binding	Papaver rhoeas
P197T	mutation confers resistance to herbicide tribenuron. Mutation results in altered secondary structure, which stabilizes an ALS tertiary conformation that prevents tribenuron binding	Papaver rhoeas

Organism	UniProt	Comment	Textmining
Papaver rhoeas	Q7X9G4	-	-