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Literature summary for 2.2.1.6 extracted from
- Purification and characterization of the catabolic alpha-acetolactate synthase from Leuconostoc mesenteroides subsp. cremonis (1995), Curr. Microbiol., 31, 316-321.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| acetate | increases activity | Leuconostoc mesenteroides |  |
| ethanol | increases activity | Leuconostoc mesenteroides | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-phosphoglycerate | noncompetitive | Leuconostoc mesenteroides | |
| ATP | noncompetitive | Leuconostoc mesenteroides | |
| phosphoenolpyruvate | noncompetitive | Leuconostoc mesenteroides | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 10 | - |
pyruvate | - |
Leuconostoc mesenteroides | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the enzyme does not require a divalent cation for activity | Leuconostoc mesenteroides |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | - |
3 * 55000, SDS-PAGE | Leuconostoc mesenteroides |
| 150000 | - |
- |
Leuconostoc mesenteroides |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | Leuconostoc mesenteroides | catabolic enzyme is involved in 2,3-butanediol pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leuconostoc mesenteroides | - |
subsp. cremonis | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Leuconostoc mesenteroides |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.844 | - |
- |
Leuconostoc mesenteroides |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate | - |
Leuconostoc mesenteroides | 2-acetolactate + CO2 | - |
? | |
| pyruvate | catabolic enzyme is involved in 2,3-butanediol pathway | Leuconostoc mesenteroides | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| trimer | 3 * 55000, SDS-PAGE | Leuconostoc mesenteroides |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.3 | - |
- |
Leuconostoc mesenteroides |
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