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Literature summary for 2.1.3.3 extracted from

  • Tokushige, K.; Hashimoto, E.; Noto, H.; Yatsuji, S.; Tobari, M.; Torii, N.; Taniai, M.; Shiratori, K.; Murayama, H.
    Clinical significance of serum ornithine carbamoyltransferase in patients with non-alcoholic steatohepatitis (2009), Hepatol. Res., 39, 939-943.
    View publication on PubMed

Application

Application Comment Organism
medicine in patients with non-alcoholic steatohepatitis, the serum levels of ornithine carbamoyltransferase and the ratios of ornithine carbamoyltransferase:alanine amino transferase and ornithine carbamoyltransferase:aspartate amino transferase are increased in parallel with the progression of on-alcoholic steatohepatitis. Especially, ornithine carbamoyltransferase and both ratios are markedly increased in hepatocellular carcinoma. As for the relationship between fibrosis grade and ornithine carbamoyxltransferase, the serum ornthine carbamoyltransferase levels and theratio of ornithine carbamoyltransferase:alanine amino transferase levels are increased in parallel with liver fibrosis. In non-alcoholic steatohepatitis patients with alanine amino transferase within normal range, about 30% show elevation of ornithine carbamoyltransferase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with non-alcoholic steatohepatitis
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Source Tissue

Source Tissue Comment Organism Textmining