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Literature summary for 2.1.2.11 extracted from

  • Pearce, M.J.; Arora, P.; Festa, R.A.; Butler-Wu, S.M.; Gokhale, R.S.; Darwin, K.H.
    Identification of substrates of the Mycobacterium tuberculosis proteasome (2006), EMBO J., 25, 5423-5432.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
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 enzyme is degraded by the proteasome. Maintenance of the physiological levels of 3-methyl-2-oxobutanoate hydroxymethyltransferase and of malonyl-CoA acyl carrier protein transacylase requires Mycobacterium proteasomal ATPase and proteasome accessory factor in addition to proteasome protease activity
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Subunits

Subunits Comment Organism
More enzyme is degraded by the proteasome. Maintenance of the physiological levels of 3-methyl-2-oxobutanoate hydroxymethyltransferase and of malonyl-CoA acyl carrier protein transacylase requires Mycobacterium proteasomal ATPase and proteasome accessory factor in addition to proteasome protease activity Mycobacterium tuberculosis