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Literature summary for 2.1.2.1 extracted from
- Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade (2015), OncoTargets Ther., 8, 1069-1074.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | isozyme SHMT2 is a possible target for anticancer therapies | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression pattern of SHMT2 in 76 breast cancer patients after modified radical mastectomy, expression analysis | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | mitochondrial isoform SHMT2 | Homo sapiens | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast cancer cell | expression patterns of SHMT2 in 76 breast cancer patients after modified radical mastectomy, immunohistochemic analysis, SHMT2 is highly expressed in breast cancer cells, and the expression level of SHMT2 is positively correlated with breast cancer grade | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| serine hydroxymethyltransferase | - |
Homo sapiens |
| SHMT | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the mitochondrial isoform SHMT2 is a crucial factor in the serine/glycine metabolism in several cancer cell types. Correlation of expression level of SHMT2 and other clinicopathological parameters in clinical breast cancer, overview | Homo sapiens |
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Release 2023.1 (January 2023)
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