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Literature summary for 2.1.1.B84 extracted from

  • Nomura, T.; Kutchan, T.M.
    Is a metabolic enzyme complex involved in the efficient and accurate control of Ipecac alkaloid biosynthesis in Psychotria ipecacuanha? (2010), Plant Signal. Behav., 5, 875-877.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Carapichea ipecacuanha 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 1alpha-(S)-N-deacetylisoipecoside Carapichea ipecacuanha the iminium cation, one of the spontaneous reaction products of 6-O-methyl-N-deacetylisoipecoside aglycon, might be an intermediate of emetine biosynthesis S-adenosyl-L-homocysteine + 6-O-methyl-N-deacetylisoipecoside
-
?
S-adenosyl-L-methionine + cephaeline Carapichea ipecacuanha
-
S-adenosyl-L-homocysteine + emetine
-
?

Organism

Organism UniProt Comment Textmining
Carapichea ipecacuanha
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Carapichea ipecacuanha
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 1alpha-(S)-N-deacetylisoipecoside
-
Carapichea ipecacuanha S-adenosyl-L-homocysteine + 6-O-methyl-N-deacetylisoipecoside
-
?
S-adenosyl-L-methionine + 1alpha-(S)-N-deacetylisoipecoside the iminium cation, one of the spontaneous reaction products of 6-O-methyl-N-deacetylisoipecoside aglycon, might be an intermediate of emetine biosynthesis Carapichea ipecacuanha S-adenosyl-L-homocysteine + 6-O-methyl-N-deacetylisoipecoside
-
?
S-adenosyl-L-methionine + cephaeline
-
Carapichea ipecacuanha S-adenosyl-L-homocysteine + emetine
-
?

Synonyms

Synonyms Comment Organism
IpeOMT1
-
Carapichea ipecacuanha

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Carapichea ipecacuanha

General Information

General Information Comment Organism
metabolism OMT1 catalyzes a step in the biosynthesis of Ipecac alkaloids, pathways overview Carapichea ipecacuanha