Literature summary for 2.1.1.96 extracted from

Warner, D.R.; Hoffman, J.L.
Suicide inactivation of thioether S-methyltransferase by ethyl vinyl sulfide (1996), Biochemistry, 35, 4480-4484.

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Inhibitors

Inhibitors	Comment	Organism	Structure
ethyl vinyl sulfide	suicide substrate, inactivation rate constant: 0.05/min, dimethyl sulfide protects	Mus musculus
methyl ethyl vinyl sulfonium	product of ethyl vinyl sulfide methylation inactivates	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + ethyl vinyl sulfide	suicide substrate leading to inactivation	Mus musculus	S-adenosyl-L-homocysteine + methyl ethyl vinyl sulfonium	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.275	-	ethyl vinyl sulfide	suicide substrate	Mus musculus

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Release 2023.1 (January 2023)