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Literature summary for 2.1.1.96 extracted from

  • Mozier, N.M.; McConnel, K.P.; Hoffman, J.L.
    S-Adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism (1988), J. Biol. Chem., 263, 4527-4531.
    View publication on PubMed
Search for more literature for 2.1.1.96

Inhibitors

Inhibitors Comment Organism Structure
S-adenosyl-L-homocysteine 0.04 mM, 50% inhibition Mus musculus
sinefungin 0.025 mM, 50% inhibition Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0004
-
 dimethyl selenide
-
 Mus musculus
0.001
-
 S-adenosylmethionine
-
 Mus musculus
0.001
-
 Dimethyl sulfide
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE, gel filtration, chromatofocusing Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-
lung
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 1,4-dithiane
-
 Mus musculus S-adenosyl-L-homocysteine + methyl-1,4-dithiane
-
 ?
S-adenosyl-L-methionine + 2-methylthioethanol
-
 Mus musculus S-adenosyl-L-homocysteine + 2,2-dimethylthioethanol
-
 ?
S-adenosyl-L-methionine + 2-methylthioethylamine
-
 Mus musculus S-adenosyl-L-homocysteine + 2,2-dimethylthioethylamine
-
 ?
S-adenosyl-L-methionine + 3-methylthiopropionaldehyde
-
 Mus musculus S-adenosyl-L-homocysteine + 3,3-dimethylthiopropionaldehyde
-
 ?
S-adenosyl-L-methionine + benzyl methyl sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + benzyl dimethyl sulfonium
-
 ?
S-adenosyl-L-methionine + diethyl sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + diethylmethylsulfonium
-
 ?
S-adenosyl-L-methionine + dimethyl selenide
-
 Mus musculus S-adenosyl-L-homocysteine + trimethylselenonium
-
 ?
S-adenosyl-L-methionine + dimethyl sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + trimethylsulfonium
-
 ?
S-adenosyl-L-methionine + dimethyl telluride
-
 Mus musculus S-adenosyl-L-homocysteine + trimethyltelluronium
-
 ?
S-adenosyl-L-methionine + ethyl vinyl sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + methyl ethyl vinyl sulfonium
-
 ?
S-adenosyl-L-methionine + methyl n-propyl sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + dimethyl n-propyl sulfonium
-
 ?
S-adenosyl-L-methionine + pentamethylene sulfide
-
 Mus musculus S-adenosyl-L-homocysteine + pentamethylenemethylsulfonium
-
 ?
S-adenosyl-L-methionine + tetrahydrothiophene
-
 Mus musculus S-adenosyl-L-homocysteine + methyltetrahydrothiophene
-
 ?
S-adenosyl-L-methionine + thiomorpholine
-
 Mus musculus S-adenosyl-L-homocysteine + methylthiomorpholine
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 28000, SDS-PAGE Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3
-
 sharp drop in activity below Mus musculus