Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | during the early log phase of extracellular growth, the enzyme shows partial localisation to the endoplasmic reticulum | Leishmania infantum | 5783 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
x * 55000, calculated from amino acid sequence | Leishmania infantum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + phospholipid olefinic fatty acid | Leishmania infantum | - |
S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania infantum | - |
clone JPCM5 MCAN/ES/98/LLM-877 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
promastigote | - |
Leishmania infantum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + phospholipid olefinic fatty acid | - |
Leishmania infantum | S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 55000, calculated from amino acid sequence | Leishmania infantum |
Synonyms | Comment | Organism |
---|---|---|
CFAS | - |
Leishmania infantum |
cyclopropane fatty acid synthetase | - |
Leishmania infantum |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme loss does not affect extracellular parasite growth, phagocytosis or early survival in macrophages, however, membrane transporter activity is defective and the null parasites are more resistant to oxidative stress | Leishmania infantum |