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Literature summary for 2.1.1.77 extracted from

  • Kern, R.; Malki, A.; Abdallah, J.; Liebart, J.C.; Dubucs, C.; Yu, M.H.; Richarme, G.
    Protein isoaspartate methyltransferase is a multicopy suppressor of protein aggregation in Escherichia coli (2005), J. Bacteriol., 187, 1377-1383.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli the enzyme might by overburdened in some physiological conditions and its overproduction may be beneficial in conditions in which protein aggregation occrus, for example during biotechnological protein overproduction or in protein aggregation diseases S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli the enzyme might by overburdened in some physiological conditions and its overproduction may be beneficial in conditions in which protein aggregation occurs, for example during biotechnological protein overproduction or in protein aggregation diseases S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate the enzyme might by overburdened in some physiological conditions and its overproduction may be beneficial in conditions in which protein aggregation occrus, for example during biotechnological protein overproduction or in protein aggregation diseases Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate the enzyme might by overburdened in some physiological conditions and its overproduction may be beneficial in conditions in which protein aggregation occurs, for example during biotechnological protein overproduction or in protein aggregation diseases Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Synonyms

Synonyms Comment Organism
PIMT
-
Escherichia coli
protein isoaspartate methyltransferase
-
Escherichia coli