Literature summary for 2.1.1.72 extracted from

Kubicek-Sutherland, J.; Heithoff, D.; Ersoy, S.; Shimp, W.; Mahan, M.
Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes (2014), Vaccine, 32, 1451-1459.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + DNA adenine	Yersinia pseudotuberculosis	-	S-adenosyl-L-homocysteine + DNA 6-methylaminopurine	-	?

Organism

Organism	UniProt	Comment	Textmining
Yersinia pseudotuberculosis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + DNA adenine	-	Yersinia pseudotuberculosis	S-adenosyl-L-homocysteine + DNA 6-methylaminopurine	-	?

Synonyms

Synonyms	Comment	Organism
Dam	-	Yersinia pseudotuberculosis
DNA adenine methyltransferase	-	Yersinia pseudotuberculosis

General Information

General Information	Comment	Organism
physiological function	the enzyme is essential for cell viability and confers potent cross-protective efficacy as well as decreased virulence and spontaneous mutation frequency	Yersinia pseudotuberculosis

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Release 2023.1 (January 2023)