Protein Variants | Comment | Organism |
---|---|---|
A719G | the mutant exhibits reduced activity compared to the wild type enzyme | Homo sapiens |
C216T | the mutant exhibits reduced activity compared to the wild type enzyme | Homo sapiens |
G238C | the mutant exhibits reduced activity compared to the wild type enzyme | Homo sapiens |
G460A | the mutant exhibits reduced activity compared to the wild type enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + a thiopurine | Homo sapiens | - |
S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P51580 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + 6-mercaptopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylmercaptopurine | - |
? | |
S-adenosyl-L-methionine + a thiopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? | |
S-adenosyl-L-methionine + azathioprine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylmercaptopurine + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TPMT | - |
Homo sapiens |