Literature summary for 2.1.1.67 extracted from

Sheffield, L.J.; Irving, P.; Gupta, A.; Byron, K.; Macrae, F.A.; Phillimore, H.; Dronavalli, M.; Rose, R.; George, P.; Walmsley, T.; Dixon, B.; Poole, S.; Dooley, M.; Sparrow, M.
Thiopurine methyltransferase and thiopurine metabolite testing in patients with inflammatory bowel disease who are taking thiopurine drugs (2009), Pharmacogenomics, 10, 1091-1099.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + 6-mercaptopurine	-	Homo sapiens	S-adenosyl-L-homocysteine + 6-methylmercaptopurine	-	?
S-adenosyl-L-methionine + 6-thioinosine 5'-monophosphate	-	Homo sapiens	S-adenosyl-L-homocysteine + 6-methylmercaptopurine ribonucleotide	-	?

Synonyms

Synonyms	Comment	Organism
thiopurine methyltransferase	-	Homo sapiens
TPMT	-	Homo sapiens

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Release 2023.1 (January 2023)