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Literature summary for 2.1.1.63 extracted from

  • Liem, L.K.; Lim, A.; Li, B.F.L.
    Specificities of human, rat and E.coli O6-methylguanine-DNA methyltransferases towards the repair of O6-methyl and O6-ethylguanine in DNA (1994), Nucleic Acids Res., 22, 1613-1619.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.63

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Homo sapiens
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA containing 6-O-ethylguanine + [protein]-L-cysteine CGC(e6G)AGCTCGCG Escherichia coli DNA lacking 6-O-ethylguanine +[protein]-S-ethyl-L-cysteine
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 ?
DNA containing 6-O-ethylguanine + [protein]-L-cysteine CGC(e6G)AGCTCGCG Homo sapiens DNA lacking 6-O-ethylguanine +[protein]-S-ethyl-L-cysteine
-
 ?
DNA containing 6-O-ethylguanine + [protein]-L-cysteine CGC(e6G)AGCTCGCG Rattus norvegicus DNA lacking 6-O-ethylguanine +[protein]-S-ethyl-L-cysteine
-
 ?
DNA containing 6-O-methylguanine + [protein]-L-cysteine
-
 Homo sapiens DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine
-
 ?
DNA containing 6-O-methylguanine + [protein]-L-cysteine CGC(m6G)CG and CGC(m6G)AGCTCGCG Escherichia coli DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine
-
 ?
DNA containing 6-O-methylguanine + [protein]-L-cysteine CGC(m6G)CG and CGC(m6G)AGCTCGCG Rattus norvegicus DNA lacking 6-O-methylguanine + [protein]-S-methyl-L-cysteine
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
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 additional information second order repair rate constants of 6-O-methyl and 6-O-ethylguanine containing substrates Escherichia coli
additional information
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 additional information second order repair rate constants of 6-O-methyl and 6-O-ethylguanine containing substrates Homo sapiens
additional information
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 additional information second order repair rate constants of 6-O-methyl and 6-O-ethylguanine containing substrates Rattus norvegicus