Application | Comment | Organism |
---|---|---|
medicine | L-dopa treatment is an acquired cause of hyperhomocysteinemia. The mechanism underlying L-dopa-related hyperhomocysteinemia is the O-methylation of the drug catalyzed by the enzyme catechol-O-methyltransferase. L-Dopa is the gold standard in the symptomatic management of Parkinsons disease, but its long-term treatment is complicated by the elevation in plasma homocysteine concentrations, due to the O-methylation by COMT | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
COMT | - |
Homo sapiens |