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Literature summary for 2.1.1.6 extracted from

  • Barnett, J.H.; Heron, J.; Ring, S.M.; Golding, J.; Goldman, D.; Xu, K.; Jones, P.B.
    Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children (2007), Am. J. Psychiatry, 164, 142-149.
    View publication on PubMed

Application

Application Comment Organism
medicine in boys there appeared to be a population shift toward higher verbal IQ with increasing Met allele dose (Val108/158Met polymorphism). The effects on IQ are significantly greater in pubertal than in prepubertal boys. In girls, there are no significant effects of genotype on cognition Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Synonyms

Synonyms Comment Organism
COMT
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Homo sapiens