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Literature summary for 2.1.1.57 extracted from

  • Ensinger, M.J.; Martin, S.A.; Paoletti, E.; Moss, B.
    Modification of the 5-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus (1975), Proc. Natl. Acad. Sci. USA, 72, 2525-2529.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information EDTA Vaccinia virus

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
-
Vaccinia virus 19013
-

Organism

Organism UniProt Comment Textmining
Vaccinia virus
-
-
-
Vaccinia virus WR
-
-
-

Purification (Commentary)

Purification (Comment) Organism
solubilized from viral core Vaccinia virus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Vaccinia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information poly(A) and internal nucleotides of RNA Vaccinia virus ?
-
?
additional information poly(A) and internal nucleotides of RNA Vaccinia virus WR ?
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA unmethylated vaccinia virus mRNA Vaccinia virus S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA methylates 2'-O-position of penultimate nucleoside of RNA, no methylation of internal sites Vaccinia virus S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA unmethylated vaccinia virus mRNA Vaccinia virus WR S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?
S-adenosyl-L-methionine + m7G(5')pppR-RNA methylates 2'-O-position of penultimate nucleoside of RNA, no methylation of internal sites Vaccinia virus WR S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Vaccinia virus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
assay at Vaccinia virus