Cloned (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae strains YBS40, YBS2, and YBS20 | Severe acute respiratory syndrome-related coronavirus |
Protein Variants | Comment | Organism |
---|---|---|
D243A | the point mutation in the ExoN domain does not significantly interfere with the N7-MTase function | Severe acute respiratory syndrome-related coronavirus |
D331A | the mutation destroys the MTase activity of nsp14 in vivo | Severe acute respiratory syndrome-related coronavirus |
D90A/E92A | the point mutation in the ExoN domain does not significantly interfere with the N7-MTase function | Severe acute respiratory syndrome-related coronavirus |
H268L | the point mutation in the ExoN domain does not significantly interfere with the N7-MTase function | Severe acute respiratory syndrome-related coronavirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome-related coronavirus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Severe acute respiratory syndrome-related coronavirus | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(guanine-N7)-methyltransferase | - |
Severe acute respiratory syndrome-related coronavirus |
N7-MTase | - |
Severe acute respiratory syndrome-related coronavirus |
nonstructural protein 14 | - |
Severe acute respiratory syndrome-related coronavirus |
nsp 14 | - |
Severe acute respiratory syndrome-related coronavirus |