Cloned (Comment) | Organism |
---|---|
complementation of knock-down HeLa S3 cells with enzymatically active N-truncated enzyme comprising residues 120-476 and being located at the nucleus, no complementation of knock-down HeLa S3 cells with enzymatically active N-truncated enzyme comprising residues 144-476 and being loacetd mainly in the cytoplasm, truncated enzymes are expresss in fusion with GFP | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of knock-down HeLa cells S3, gene inactivation by small interference RNA in HeLa cells results in apoptosis | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | nuclear localization is required for cell viability, targeting localization signal sequences are 80KKRK, 103KKRKR, and 126KRK | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | Homo sapiens | essential for cell viability | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Homo sapiens | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? | |
S-adenosyl-L-methionine + G(5')pppR-RNA | essential for cell viability | Homo sapiens | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mRNA cap methyltransferase | - |
Homo sapiens |