Literature summary for 2.1.1.5 extracted from

Finkelstein, J.D.; Martin, J.J.
Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine (1984), Biochem. Biophys. Res. Commun., 118, 14-19.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	product inhibition	Rattus norvegicus
S-adenosyl-L-ethionine	irreversible, S-adenosyl-L-homocysteine and L-homocysteine prevent, but not DL-homocysteine, GSH, DTT or L-cysteine	Rattus norvegicus
S-adenosyl-L-methionine	irreversible, S-adenosyl-L-homocysteine and L-homocysteine prevent, not DL-homocysteine, GSH, DTT or L-cysteine	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N,N,N-trimethylglycine + L-homocysteine	-	Rattus norvegicus	N,N-dimethylglycine + L-methionine	-	?

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Release 2023.1 (January 2023)