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Literature summary for 2.1.1.45 extracted from

  • Nielsen, E.; Cella, R.
    Thymidylate synthase in plant cells: Kinetic and molecular properties of the enzyme from Daucus carota L. cell cultures (1988), Plant Cell Physiol., 29, 503-508.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
5-fluoro-2'-deoxyuridylic acid
-
Daucus carota

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
185000
-
gel filtration Daucus carota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP Daucus carota
-
dihydrofolate + dTMP
-
?

Organism

Organism UniProt Comment Textmining
Daucus carota
-
carrot, wild and culture form
-

Purification (Commentary)

Purification (Comment) Organism
partially Daucus carota

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP
-
Daucus carota dihydrofolate + dTMP
-
?
5,10-methylenetetrahydrofolate + dUMP
-
Daucus carota dihydrofolate + dTMP
-
r