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Literature summary for 2.1.1.45 extracted from

  • Kanai, F.; Kaneko, T.; Morishima, H.; Isshiki, K.; Takita, T.; Takeuchi, T.; Umezawa, H.
    Vanoxonin, a new inhibitor of thymidylate synthetase. III. Inhibition of thymidylate synthetase by vanoxonin-vanadium complex (1985), J. Antibiot., 38, 39-50.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
vanoxonin-vanadium
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP Mus musculus
-
dihydrofolate + dTMP
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
Ehrlich ascites carcinoma cells
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP
-
Mus musculus dihydrofolate + dTMP
-
?
5,10-methylenetetrahydrofolate + dUMP
-
Mus musculus dihydrofolate + dTMP
-
r