Literature summary for 2.1.1.41 extracted from

Kaneshiro, E.; Johnston, L.; Nkinin, S.; Romero, B.; Giner, J.
Sterols of Saccharomyces cerevisiae erg6 knockout mutant expressing the Pneumocystis carinii S-adenosylmethionine sterol C-24 methyltransferase (SAM SMT) (2015), J. Eukaryot. Microbiol., 62, 298-306 .

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Organism

Organism	UniProt	Comment	Textmining
Pneumocystis carinii	Q96WX4	catalyzes the reactions of both EC 2.1.1.142 and EC 2.1.1.41	-
Pneumocystis carinii B80	Q96WX4	catalyzes the reactions of both EC 2.1.1.142 and EC 2.1.1.41	-

Subunits

Subunits	Comment	Organism
?	x * 43000, SDS-PAGE	Pneumocystis carinii

Synonyms

Synonyms	Comment	Organism
Erg6	-	Pneumocystis carinii
SAM:SMT	-	Pneumocystis carinii

General Information

General Information	Comment	Organism
physiological function	enzyme transfers either one or two methyl groups to the C-24 position of the sterol side chain producing both C28 and C29 24-alkylsterols in approximately the same proportions. Expression of SAM:SMT in a Saccharomyces cerevisiae Erg6 mutant restores its ability to produce ergosterol as the major sterol, and also results in low levels of C29 sterols such as pneumocysterol	Pneumocystis carinii

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Release 2023.1 (January 2023)